Christopher A. Price
- Professeur titulaire
-
Faculté de médecine vétérinaire - Département de biomédecine vétérinaire
Pavillon 3200, rue Sicotte - Aile A office 1429
Travail 1 : 450 773-8521 #8261
Web : ResearchGate
Web : LinkedIn
Web : Google Scholar
Biography
BSc, University of Nottingham
PhD, University of Edinburgh
Post-doc: Wallaceville Animal Research Centre, New Zealand.
Affiliations
Education Programs
- Health Sciences
- Health Sciences
Courses
- MMV66751 Séminaires de recherche en sciences vétérinaires 1
- MMV66751 Séminaires de recherche en sciences vétérinaires 1
- MMV66752 Séminaires de recherche en sciences vétérinaires 2
- MMV66752 Séminaires de recherche en sciences vétérinaires 2
- MMV66753 Séminaires de recherche en sciences vétérinaires 3
- MMV66753 Séminaires de recherche en sciences vétérinaires 3
- MMV70011 Séminaires de recherche en sciences vétérinaires 1
- MMV70011 Séminaires de recherche en sciences vétérinaires 1
- MMV70012 Séminaires de recherche en sciences vétérinaires 2
- MMV70012 Séminaires de recherche en sciences vétérinaires 2
- MMV70013 Séminaires de recherche en sciences vétérinaires 3
- MMV70013 Séminaires de recherche en sciences vétérinaires 3
- MMV70014 Séminaires de recherche en sciences vétérinaires 4
- MMV70014 Séminaires de recherche en sciences vétérinaires 4
- MMV70015 Séminaires de recherche en sciences vétérinaires 5
- MMV70015 Séminaires de recherche en sciences vétérinaires 5
- MMV70016 Séminaires de recherche en sciences vétérinaires 6
- MMV70016 Séminaires de recherche en sciences vétérinaires 6
Expertises
The long-term goals of my lab are to understand better the endocrine and paracrine factor that control ocarian follicle development, for a better control of fertility in cattle.
To do so, we use mainly in-vitro appoaches with ruminant granulosa and theca cell cultures to investigate the mechanisms of action of various hormines and growth factors on cell health and function.
Student supervision Expand all Collapse all
Cycle : Doctoral
Grade : Ph. D.
Cycle : Master's
Grade : M. Sc.
Cycle : Doctoral
Grade : Ph. D.
Cycle : Doctoral
Grade : Ph. D.
Cycle : Master's
Grade : M. Sc.
Cycle : Master's
Grade : M. Sc.
Research projects Expand all Collapse all
Réseau Québécois en Reproduction Projet de recherche au Canada / 2024 - 2031
Novel mechanisms of theca cell growth in the ovarian follicle of cattle Projet de recherche au Canada / 2021 - 2029
The role of 'FNDC' adipokines in ovarian function in cattle. Projet de recherche au Canada / 2023 - 2025
Réseau Québecois en Reproduction (RQR) Projet de recherche au Canada / 2017 - 2025
Nouvelles cibles moléculaires dans le but d’améliorer la fonction ovarienne chez la vache laitière Projet de recherche au Canada / 2017 - 2022
THE ROLE OF THECA CELLS IN OVARIAN FOLLICLE ATRESIA IN CATTLE Projet de recherche au Canada / 2015 - 2022
The role of theca cells in ovarian follicle atresia in cattle - Supplément d'accélération Projet de recherche au Canada / 2015 - 2019
REGROUPEMENT STRATEGIQUE - RESEAU QUEBECOIS EN REPRODUCTION (RQR) Projet de recherche au Canada / 2011 - 2018
EFFECT OF FUNGAL TOXINS ON FERTILITY IN DAIRY CATTLE Projet de recherche au Canada / 2012 - 2016
NOVEL REGULATORS OF GRANULOSA CELL FUNCTION Projet de recherche au Canada / 1994 - 2016
LIQUID SCINTILLATION COUNTER Projet de recherche au Canada / 2013 - 2015
NOUVELLES VOIES VERS L'EMBRYON SAIN CHEZ LES ANIMAUX DE CONSOMMATION Projet de recherche au Canada / 2011 - 2015
NOVEL REGULATORS OF GRANULOSA CELL FUNCTION Projet de recherche au Canada / 2009 - 2014
NOUVELLES VOIES VERS L'EMBRYON SAIN CHEZ LES ANIMAUX DE CONSOMMATION Projet de recherche au Canada / 2011 - 2013
SAFETY OF ESTRADIOL USE DURING SUPEROVULATION IN LACTATING DAIRY COWS Projet de recherche au Canada / 2010 - 2010
INCUBATOR SUITE Projet de recherche au Canada / 2009 - 2009
Publications Expand all Collapse all
Buratini J, Dellaqua TT, Lima PF, Renzini MM, Canto MD, Price CA. Oocyte secreted factors control genes regulating FSH signaling and the maturation cascade in cumulus cells: the oocyte is not in a hurry. JARG doi.org/10.1007/s10815-023-02822-y
Reyes-Perea AD, Guerrero-Netro HM, Meza-Serrano E, Estienne A, Price CA (2023) The mycotoxin de-epoxy-deoxynivalenol (DOM-1) increases endoplasmic reticulum stress in ovarian theca cells. Toxins 15: 228. doi.org/10.3390/toxins15030228
Daudon M, Ramé C, Price CA*, Dupont J* (2023) Irisin modulates glucose metabolism and inhibits steroidogenesis in bovine granulosa cells. Reproduction 165:533-542. https://doi.org/10.1530/REP-22-0404
Wang S, Yao Q, Zhao F, Cui W, Price CA, Wang Y, Lv J, Tang H, Jiang Z (2023). 1α,25(OH)2D3 promotes the autophagy of porcine ovarian granulosa cells as a protective mechanism against ROS through BNIP3/PINK1 pathway. Int J Mol Sci 24: 4364. doi.org/10.3390/ijms24054364
Biolková M, Moore T, Schindler K, Swann K, Vail A, Flook L, Dick H, Fitzharris G, Price C*, Spears N* (2023). Investigation of potential gender bias in the peer review system at Reproduction. Learned Publishing 36: 25-30. https://doi.org/10.1002/leap.1537.
Relav L, dos Santos, EC, Zamberlam G, Price CA. Abundance of dual specificity phosphatase (DUSP) 1 and DUSP6 mRNA is regulated by Hippo signaling in bovine pre-ovulatory granulosa cells. Reproductive Sciences. https://doi.org/10.1007/s43032-022-01142-3.
Goetten ALF, Koch J, Rocha CC, Mezzalira A, Price CA, Portela VM, Barreta MH. (2023) Expression profile of key genes involved in DNA repair mechanisms in bovine cumulus cells cultured with bovine serum albumin or fetal calf serum. Reproductive Biology 23: 100709.
Daudon M, Rame C, Estienne A, Price CA*, Dupont J*. (2022) Impact of Fibronectin type III Domain-Containing Family in the changes in metabolic and hormonal profiles during peripartum period in dairy cows. Frontiers in Vet Sci 9:960778. DOI 10.3389/fvets.2022.960778.
Daudon M, Bigot Y, Dupont J*, Price CA* (2022) Irisin and the fibronectin type III domain-containing family: Structure, signalling and role in female reproduction. Reproduction 164: R1-R9.
Estienne AE, Relav L, Benkoura M, Monniaux D, Morin F, Fabre S, Price CA (2022) Endothelial cell-derived fibroblast growth factor-18 regulates ovarian function in sheep. J Cell Physiol. 237:2528-2538. http://doi.org/10.1002/jcp.30718
Liu N, Wang S, Yao Q, Li Y, Hu H, Xiaorong T, Ran H, Price C, Jiang ZL (2022) Activin A attenuates apoptosis of granulosa cells in atretic follicles through ERβ-induced autophagy. Reprod Dom Anim. 57:625-634.
Dos Santos EC, Lalonde-Larue A, Antoniazzi AQ, Barreta MH, Price CA, Gonçalves PBD, Portela VM, Zamberlam GO (2022) YAP signaling in preovulatory granulosa cells is critical for the functioning of the EGF network during ovulation. Mol Cell Endo 541:111524
Relav L, Price CA (2021) Regulation of Dual Specificity Phosphatases by Fibroblast Growth Factor signaling pathways in bovine granulosa cells. Reproduction 162: 367-374. (http://dx.doi.org/10.1530/REP-21-0270)
Juengel JL, Cushman RA, Dupont J, Fabre S, Lea RG, Martin GB, Mossa F, Pitman JL, Price CA, Smith P (2021) The ovarian follicle of ruminants: the path from conceptus to adult. Reprod Fertil Devel. 33: 621-642. https://doi.org/10.1071/RD21086
Relav L, Estienne A, Price CA (2021) Dual-specificity phosphatase 6 (DUSP6) mRNA and protein abundance is regulated by fibroblast growth factor 2 in sheep granulosa cells and inhibits c-Jun N-terminal kinase (MAPK8) phosphorylation. Mol Cell Endo 531: 111297. https://doi.org/10.1016/j.mce.2021.111297
Guerro-Netro H, Barreta M, Costa E, Goetten A, Dupras R, Mills L, Koch J, Portela VM, Price CA, Chorfi Y (2021) Effects of the mycotoxin metabolite de-epoxy-deoxynivalenol (DOM-1) on embryo development and sperm motility in cattle. J Appl Toxicol 41:1180-1187. DOI: 10.1002/jat.4102
Han P, Relav L, Price CA (2020) Regulation of the early growth response-1 binding protein NAB2 in bovine granulosa cells and effect on connective tissue growth factor expression. Mol Cell Endo 518: 111041. doi.org/10.1016/j.mce.2020.111041
Jaton C, Schenkel FS, Chud TCS, Malchiodi F, Sargolzaei M, Price CA, Cánovas A,, Baes C, Miglior F. (2020) Genetic and genomic analyses of embryo production in dairy cattle. Reproduction, Fertility and Development 32, 50–55. doi.org/10.1071/RD19275
Sahmi F, Sahmi M, Gévry N, Sahadevan P, Allen BG, Price CA. (2019) A putative protein:RNA complex regulates post-transcriptional processing of cytochrome P450 aromatase (CYP19A1) in bovine granulosa cells. Mol Reprod Develop 86:1901-1908. https://doi.org/10.1002/mrd.23289
Zhang N, Wang L, Juo G, Tang X, Ma L, Zheng Y, Liu S, Price CA, Jiang Z (2019) Arachidonic acid regulation of intracellular signaling pathways and target gene expression in bovine ovarian granulosa cells. Animals 9: 374.
Estienne A, Portela VM, Choi Y, Zamberlam G, Boerboom D, Roussel V, Meinsohn MC, Brännström M, Curry TE, Jo M, Price CA. (2019) The endogenous hydrogen sulfide generating system regulates ovulation. Free Rad Biol Med 138:43-52. doi.org/10.1016/j.freeradbiomed.2019.03.028
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