Imourana Alassane-Kpembi
- Professeur adjoint
-
Faculté de médecine vétérinaire - Département de biomédecine vétérinaire
Pavillon 3200, rue Sicotte - Aile A office 3976
Travail 1 : 450 733-8521 #36481
Travail 2 : 514 345-8521 #36481
Web : ResearchGate
Web : LinkedIn
Expertises
Research projects Expand all Collapse all
Appui au Centre de recherche en infectiologie porcine et avicole (CRIPA) Projet de recherche au Canada / 2022 - 2029
Centre de Recherche en Infectiologie Porcine et Avicole (CRIPA) Projet de recherche au Canada / 2022 - 2029
Appui au Centre de recherche en infectiologie porcine et avicole (CRIPA) Projet de recherche au Canada / 2022 - 2029
Appui au Centre de recherche en infectiologie porcine et avicole (CRIPA) Projet de recherche au Canada / 2022 - 2029
Appui au Centre de recherche en infectiologie porcine et avicole (CRIPA) Projet de recherche au Canada / 2022 - 2029
Deciphering the toxicity of zearalenone congeners in pigs Projet de recherche au Canada / 2021 - 2027
Deciphering the toxicity of zearalenone congeners in pigs Projet de recherche au Canada / 2021 - 2027
Nouvelles Initiatives du CRIPA en partenariat avec IRSST Projet de recherche au Canada / 2022 - 2025
Appui au Centre de recherche en infectiologie porcine et avicole (CRIPA) Projet de recherche au Canada / 2022 - 2025
Toxicité résiduelle et stabilité à la digestion de la zéaralenone-14-phosphate chez le porc Projet de recherche au Canada / 2022 - 2023
Publications Expand all Collapse all
Alassane-Kpembi, I., C. Canlet, M. Tremblay-Franco, F. Jourdan, M. Chalzaviel, P. Pinton, A. M. Cossalter, C. Achard, M. Castex, S. Combes, A. P. L. Bracarense and I. P. Oswald (2020). "(1)H-NMR metabolomics response to a realistic diet contamination with the mycotoxin deoxynivalenol: Effect of probiotics supplementation." Food Chem Toxicol 138: 111222.
Gauthier, T., C. Duarte-Hospital, J. Vignard, E. Boutet-Robinet, M. Sulyok, S. P. Snini, I. Alassane-Kpembi, Y. Lippi, S. Puel, I. P. Oswald and O. Puel (2020). "Versicolorin A, a precursor in aflatoxins biosynthesis, is a food contaminant toxic for human intestinal cells." Environ Int 137: 105568.
Fremy, J. M., I. Alassane-Kpembi, I. P. Oswald, B. Cottrill and H. P. Van Egmond (2019). "A review on combined effects of moniliformin and co-occurring Fusarium toxins in farm animals." World Mycotoxin J 12(3): 281-291.
Alassane-Kpembi I, Pinton P, Oswald IP. (2019) Effects of Mycotoxins on the Intestine. Toxins 2019, 11(3), 159.
Aupanun S, Phuektes P, Poapolathep S, Alassane-Kpembi I, Oswald IP, Poapolathep A. Individual and combined cytotoxicity of major trichothecenes type B, deoxynivalenol, nivalenol, and fusarenon-X on Jurkat human T cells. Toxicon 160:29-37.
Alassane-Kpembi I, Pinton P, Hupé JF, Neves M, Lippi Y, Combes S, Castex M, Oswald IP. (2018) Saccharomyces cerevisiae Boulardii Reduces the Deoxynivalenol-Induced Alteration of the Intestinal Transcriptome. Toxins 2018, 10(5), 199.
Le TH, Alassane-Kpembi I, Oswald IP, Pinton P (2018) Analysis of the interactions between environmental and food contaminants, cadmium and deoxynivalenol, in different target organs. Sci Total Environ. 622-623:841-848.
Alassane-Kpembi I, Gerez JR, Cossalter AM, Neves M, Laffitte J, Naylies C, Lippi Y, Kolf-Clauw M, Bracarense APL, Pinton P, Oswald IP (2017) Intestinal toxicity of the type B trichothecene mycotoxin fusarenon-X: whole transcriptome profiling reveals new signaling pathways. Sci Rep. 7(1):7530
Alassane-Kpembi I, Puel O, Pinton P, Cossalter AM, Chou TC, Oswald IP (2017) Co-exposure to low doses of the food contaminants deoxynivalenol and nivalenol has a synergistic inflammatory effect on intestinal explants. Arch Toxicol 91(7):2677-2687
Alassane-Kpembi I, Schatzmayr G, Taranu I, Marin D, Puel O, Oswald IP. (2016) Mycotoxins co-contamination: Methodological aspects and biological relevance of combined toxicity studies. Crit Rev Food Sci Nutr 57(16):3489-3507.
Tannous J, Snini SP, El Khoury R, Canlet C, Pinton P, Lippi Y, Alassane-Kpembi I, Gauthier T, El Khoury A, Atoui A et al (2017) Patulin transformation products and last intermediates in its biosynthetic pathway, E- and Z-ascladiol, are not toxic to human cells. Arch Toxicol 91(6):2455-2467
Alassane-Kpembi I, Puel O, Oswald IP. 2015. Toxicological interactions between the mycotoxins deoxynivalenol, nivalenol and their acetyl derivatives in intestinal epithelial cells. Arch Toxicol 89: 1337-1346.
Cheat S., Gerez J.R., Cognié J., Alassane-Kpembi I., Bracarense A.P.F.L., Raymond-Letron I., Oswald I.P., Kolf-Clauw M. 2015. Nivalenol has a greater impact than deoxynivalenol on pig jejunum mucosa in vitro on explants and in vivo on intestinal loops. Toxins 7 :1945-1961.
Alassane-Kpembi, I., Kolf-Clauw, M., Gauthier, T., Abrami, R., Abiola, F.A., Oswald, I.P., Puel, O., 2013. New insights into mycotoxin mixtures: The toxicity of low doses of Type B trichothecenes on intestinal epithelial cells is synergistic. Toxicol Appl Pharmacol 272, 191-198.
Kolf-Clauw, M., Sassahara, M., Lucioli, J., Rubira-Gerez, J., Alassane-Kpembi, I., Lyazhri, F., Borin, C., Oswald, I.P., 2013. The emerging mycotoxin, enniatin B1, down-modulates the gastrointestinal toxicity of T-2 toxin in vitro on intestinal epithelial cells and ex vivo on intestinal explants. Arch Toxicol 87, 2233-41.
Payros D, Alassane-Kpembi I., Pierron A, Loiseau N, Pinton P, Oswald IP (2016) Toxicology of deoxynivalenol and its acetylated and modified forms. Arch Toxicol 90(12):2931-2957
Pierron A, Alassane-Kpembi I, Oswald I P. (2016) Impact of mycotoxin on immune response and consequences for pig health. Animal Nutrition 2, 63-68.
Pierron, A., Alassane-Kpembi, I., Oswald, I.P. (2016) Impact of two mycotoxins deoxynivalenol and fumonisin on pig intestinal health. Porcine Health Manag 2, 1-8.
Communications Expand all Collapse all
Alassane-kpembi I, Pinton P, Puel O, Chou T-C, Oswald IP. Effet cocktail des mycotoxines du groupe des trichothécènes B sur la santé intestinale du porc. 50èmes Journées de la Recherche Porcine, Paris Espace Reuilly (France), 5-6 Février 2018.
Alassane-Kpembi I and Oswald IP. Mycotoxins in feed – Impact on gut health and implications for pig production. Pig Veterinary Society 2017 Autumn Meeting, Leeds (UK), 8-9 November 2017.
Alassane-Kpembi I, Pinton P, Puel O, Chou T-C and Oswald IP. Co-exposure to low doses of the type B Trichothecenes synergistically impairs the intestinal health. 39th Mycotoxin Workshop, Bydgoszcz (Poland), 19-21 June 2017.
Alassane-Kpembi I, Pierron A, Pinton P, and Oswald IP. Genome-wide analysis of gene expression: a tool to investigate the toxicity of mycotoxins. WMFmeetsIUPAC2016 Winnipeg (Canada), June 7, 2016.
Alassane-Kpembi I and Oswald IP. Impact of mycotoxins on immune response and consequences for pig health. Keynote lecture Taiwan Mycotoxin Forum, National Chia-Yi University (Taiwan), May 12, 2016.
Alassane-Kpembi I, Puel O, and Oswald IP. The issue of toxicological interactions in in vitro assessment of the combined toxicity of mycotoxins. 2nd FOODSEG Symposium Safe Food for Europe: Recent scientific and regulatory developments, Bucharest (Romania), 14-15 June 2013.
Alassane-Kpembi I, Puel O, and Oswald IP. New insights into mycotoxin mixtures: the toxicity of low doses of Type B trichothecenes against intestinal epithelial cells is synergistic 35th Mycotoxin Workshop, Ghent (Belgium), 22-24 May 2013.
Alassane-Kpembi I, Puel O, and Oswald IP. The type of interaction between type B trichothecenes on the intestine varies with the dose. 12th European Fusarium Seminar, Bordeaux (France), 12-16 May 2013.
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