Marcelo Gottschalk
- Professeur titulaire
-
Faculté de médecine vétérinaire - Département de pathologie et microbiologie
Pavillon 3200, rue Sicotte - Aile A office 3119-2
Travail 1 : 450 773-8521 #8374
Télécopieur : 450 778-8108
D.M.V.
1982
, Université de Buenos Aires (Argentine)
Ph.D.
1991
, Immunologie, Microbiologie , Université de Montréal (Canada)
Docteur Honoris Causa
2018
, Bactériologie , Ghent University (Belgique)
Expertises
- Microbiology
- Bactériologie
Responsabilities and outreach Expand all Collapse all
Student supervision Expand all Collapse all
Cycle : Master's
Grade : M. Sc.
Cycle : Doctoral
Grade : Ph. D.
Cycle : Doctoral
Grade : Ph. D.
Cycle : Doctoral
Grade : Ph. D.
Cycle : Master's
Grade : M. Sc.
Research projects Expand all Collapse all
Decoding the Mechanisms of Beta-Lactam Resistance in Streptococcus suis: A Genomic, Structural and Epidemiological Analysis. Projet de recherche au Canada / 2024 - 2030
Appui au Centre de recherche en infectiologie porcine et avicole (CRIPA) Projet de recherche au Canada / 2022 - 2029
Appui au Centre de recherche en infectiologie porcine et avicole (CRIPA) Projet de recherche au Canada / 2022 - 2029
Appui au Centre de recherche en infectiologie porcine et avicole (CRIPA) Projet de recherche au Canada / 2022 - 2029
Appui au Centre de recherche en infectiologie porcine et avicole (CRIPA) Projet de recherche au Canada / 2022 - 2029
Centre de Recherche en Infectiologie Porcine et Avicole (CRIPA) Projet de recherche au Canada / 2022 - 2029
Studies on the pathogenesis of the infections caused by Streptococcus suis Projet de recherche au Canada / 2022 - 2028
Conception d’un nouveau vaccin comme solution de rechange à l’utilisation d’antimicrobiens pour le contrôle de Streptococcus suis_Novel vaccine design as an alternative to antimicrobial use for preventing and controlling the swine and zoonotic agent Stre Projet de recherche au Canada / 2024 - 2026
Nouvelles Initiatives du CRIPA en partenariat avec IRSST Projet de recherche au Canada / 2022 - 2026
Appui au Centre de recherche en infectiologie porcine et avicole (CRIPA) Projet de recherche au Canada / 2022 - 2025
GlycoNet - Réseau Canadien de la Glycomique - A new generation glycoconjugate vaccine against Streptococcus suis to reduce the use of antimicrobials in swine production Projet de recherche au Canada / 2022 - 2024
Acquisition of an ultracentrifuge to support research in the field of veterinary infectious diseases Projet de recherche au Canada / 2021 - 2023
Plan de financement_Évaluation et amélioration des vaccins autogènes contre Streptococcus suis utilisés chez les truies Projet de recherche au Canada / 2019 - 2023
Novel vaccine design as an alternative to antimicrobial use for preventing and controlling the swine and zoonotic agent Streptococcus suis Projet de recherche au Canada / 2019 - 2023
Novel vaccine design as an alternative to antimicrobial use for preventing and controlling the swine and zoonotic agent streptococcus suis Projet de recherche au Canada / 2019 - 2023
Centre de Recherche en infectiologie porcine et avicole (CRIPA) / Regroupements stratégiques Projet de recherche au Canada / 2019 - 2023
Plan de transfert de connaissances_Évaluation et amélioration des vaccins autogènes contre Streptococcus suis utilisés chez les truies Projet de recherche au Canada / 2019 - 2023
STUDIES ON THE PATHOGENESIS OF THE INFECTION CAUSED BY STREPTOCOCCUS SUIS Projet de recherche au Canada / 2015 - 2023
Evaluation and improvement of Streptococcus suis bacterins Projet de recherche au Canada / 2020 - 2022
Evaluation and improvement of Streptococcus suis bacterins” (OP 19-006) Projet de recherche au Canada / 2019 - 2022
4th International Workshop on Streptococcus suis, an emerging human threat Projet de recherche au Canada / 2018 - 2022
Glycodendrimèresomes: une nouvelle génération de liposomes pour renforcer la réponse immunitaire induite par des vaccins sous-unitaires Projet de recherche au Canada / 2017 - 2022
Supplément COVID-19 CRSNG_STUDIES ON THE PATHOGENESIS OF THE INFECTION CAUSED BY STREPTOCOCCUS SUIS Projet de recherche au Canada / 2020 - 2021
Les bactéries commensales du porc productrices de bactériocines comme une alternative aux antibiotiques pour contrer les infections bactériennes chez le porc Projet de recherche au Canada / 2017 - 2020
CENTRE DE RECHERCHE EN INFECTIOLOGIE PORCINE ET AVICOLE (CRIPA) Projet de recherche au Canada / 2013 - 2020
Acquisition of a highspeed highvolume floor centrifuge to support research in the field of veterinary infectious diseases Projet de recherche au Canada / 2017 - 2019
DEVELOPMENT OF A SUB-UNIT VACCINE TO PROTECT SWINE AGAINST THE INFECTIONS CAUSED BY STREPTOCOCCUS SUIS Projet de recherche au Canada / 2015 - 2018
La portion C-terminale de la protéine P97 de Mycoplasma hyopneumoniae: une nouvelle molécule adjuvante à des fins vaccinales Projet de recherche au Canada / 2014 - 2017
CANADA-CHINA STUDIES ON THE EMERGING ZOONOTIC AGENT STREPTOCOCCUS SUIS Projet de recherche au Canada / 2013 - 2017
Tailor-made nanoparticles: A novel platform technology for antigen delivery Projet de recherche au Canada / 2016 - 2016
BEAD-BASED MULTIPLEXING TECHNOLOGY ('LUMINEX') FOR MULTIDISCIPLINARY STUDIES IN VETERINARY MEDECINE Projet de recherche au Canada / 2014 - 2016
GLYCODENDRIMÈRES POUR L'INHIBITION DE L'INFECTION PORCINE PAR LA BACTÉRIE STREPTOCOCCUS SUIS SÉROTYPE 2 Projet de recherche au Canada / 2013 - 2016
STUDIES ON THE PATHOGENESIS OF THE INFECTIONS CAUSED BY STREPTOCOCCUS SUIS Projet de recherche au Canada / 1996 - 2016
DEVELOPMENT OF A SNUB-UNIT VACCINE TO PROTECT SWINE AGAINST THE INFECTIONS CAUSED BY STREPTOCOCCUS SUIS Projet de recherche au Canada / 2014 - 2015
STUDIES ON THE PATHOGENESIS OF THE INFECTIONS CAUSED BY STREPTOCOCCUS SUIS Projet de recherche au Canada / 2009 - 2015
CENTRE DE RECHERCHE EN INFECTIOLOGIE PORCINE ET AVICOLE (CRIPA) Projet de recherche au Canada / 2013 - 2014
FREEZE-DRYER Projet de recherche au Canada / 2012 - 2014
CENTRE DE RECHERCHE EN INFECTIOLOGIE DU PORC (CRIP) Projet de recherche au Canada / 2006 - 2014
ETUDES IN VIVO SUR LA CO-INFECTION ENTRE LE VIRUS SRRP ET STREPTOCOCCUS SUIS CHEZ LE PORC Projet de recherche au Canada / 2012 - 2013
AN AUTOMATED CELL COUNTER FOR IMMUNOLOGICAL STUDIES Projet de recherche au Canada / 2009 - 2009
A REAL-TIME POLYMERASE CHAIN REACTION (PCR) SYSTEM FOR STUDIES ON HOST-PATHOGEN INTERACTIONS Projet de recherche au Canada / 2008 - 2008
Publications Expand all Collapse all
Roy D, Grenier D, Segura M, Mathieu-Denoncourt A, Gottschalk M. Recruitment of Factor H to the Streptococcus suis Cell Surface is Multifactorial. Pathogens (Basel, Switzerland). 2016;5(3).
Auger JP, Fittipaldi N, Benoit-Biancamano MO, Segura M, Gottschalk M. Virulence Studies of Different Sequence Types and Geographical Origins of Streptococcus suis Serotype 2 in a Mouse Model of Infection. Pathogens (Basel, Switzerland). 2016;5(3).
Auger, J.P., N. Meekhanon, M. Okura, M. Osaki, M. Gottschalk, T. Sekizaki, D. Takamatsu. 2015. Recovery of Streptococcus suis serotype 2 capsule in vivo. Emerging Infectious Diseases.
Okura, M., T. Nozawa, T. Watanabe, I. Nakagawa, D. Takamatsu, M. Osaki, T. Sekizaki, M. Gottschalk, S. Hamada, F. Maruyama. 2015. Miscellaneous genome sequencing reveals the characteristic genes of groups potentially hazardous to humans and the spread of antibiotic-resistance genes in Streptococcus suis. Journal of Bacteriology.
Athey T.B., S. Teatero, D. Takamatsu, J. Wasserscheid, K. Dewar, M. Gottschalk, N. Fittipaldi. Population structure and antimicrobial resistance profiles of Streptococcus suis serotype 2 sequence type 25 strains. PLoS One. 11: e0150908.
Hatrongjit, R., A. Kerdsin, M. Gottschalk, S. Hamada, K. Oishi, Y. Akeda. Development of a multiplex pcr assay to detect the major clonal complexes of Streptococcus suis relevant to human infection. Journal of Medical Microbiology. doi: 10.1099/jmm.0.000239.
Van Calsteren, M.R., G. Goyette-Desjardins, F. Gagnon, M. Okura, D. Takamatsu, R. Roy, M. Gottschalk, M. Segura. Explaining the serological characteristics of Streptococcus suis serotypes 1 and 1/2 from their capsular polysaccharide structure and biosynthesis. Journal of Biological Chemistry. Pii: jbc.M115.700716.
Sánchez Del Rey, V., J.F. Fernández-Garayzábal, L. Domínguez, M. Gottschalk, A.I. Vela. Screening of virulence-associated genes as a molecular typing method for characterization of Streptococcus suis isolates recovered from wild boars and pigs. Veterinary Journal. pii: S1090-0233(15)00478-5.
Vaillancourt, K., G. LeBel, M. Frenette, N. Fittipaldi, M. Gottschalk, D. Grenier. Purification and Characterization of Suicin 65, a Novel Class I Type B Lantibiotic Produced by Streptococcus suis. PLoS One. 10:e0145854.
Haas, B., K. Vaillancourt, L. Bonifait, M. Gottschalk, D. Grenier. Hyaluronate lyase activity of Streptococcus suis serotype 2 and modulatory effects of hyaluronic acid on the bacterium’s virulence properties. BMC Research Notes. 8: 722.
Meshkibaf, S., J. Fritz, M. Gottschalk, S.O. Kim. Preferential production of G-CSF by a protein-like Lactobacillus rhamnosus GR-1 secretory factor through activating TLR2-dependent signaling events without activation of JNKs. BMC Microbiology. 15: 238.
Auger, J.-P., M. Christodoulides, M. Segura, J. Xu, M. Gottschalk. Interactions of Streptococcus suis serotype 2 with human meningeal cells and astrocytes. BMC Research Notes. 8: 607.
Gottschalk, M., S. Lacouture. 2015. Canada : Distribution of Streptococcus suis (from 2012 to 2014) and Actinobacillus pleuropneumoniae (from 2011 to 2014) setorypes isolated from diseased pigs. Canadian Veterinary Journal. 56: 1093-1094. PMID: 26483588
Morales, B., Á. Ruiz, S. Lacouture, M. Gottschalk. Clonal distribution of Streptococcus suis isolated from diseased pigs in the central region of Chile. Canadian Journal of Veterinary Research. 79: 343-6.
Siqueira Soares, T.C., M. Gottschalk, S. Lacouture, J. Megid, P.E. Martins Ribolla, J.C. de Figueiredo Pantoja, A.C. Paes. 2015. Streptococcus suis in employees and the environment of swine slaughterhouses in São Paulo, Brazil: Occurrence, risk factors, serotype distribution, and antimicrobial susceptibility. The Canadian Journal of Veterinary Research. 79: 279-284.
Hatrongjit, R., A. Kerdsin, M. Gottschalk, D. Takeuchi, S. Hamada, K. Oishi, Y. Akeda. First human case report of sepsis due to infection with Streptococcus suis serotype 31 in Thailand. BMC Infectious Diseases. 15: 392.
Athey, T.B., J.P. Auger, S. Teatero, A. Dumesnil, D. Takamatsu, J. Wasserscheid, K. Dewar, M. Gottschalk, N. Fittipaldi. 2015. Complex population structure and virulence differences among serotype 2 Streptococcus suis strains belonging to sequence type 28. PLoS One. 10: e0137760.
Kerdsin, A., R. Hatrongjit, M. Gottschalk, D. Takeuchi, S. Hamada , Y. Akeda, K. Oishi. 2015. Emergence of Streptococcus suis serotype 9 infection in humans. Journal of Microbiology, Immunology and Infection. pii: S1684-1182(15)00822-1.
Pérez-Sancho, M., A.I. Vela, T. Garcia-Seco, M. Gottschalk, L. Dominguez, J.F. Fernández- Garayzábal. Assessment of MALDI-TOF MS as alternative tool for Streptococcus suis identification. Frontiers in Public Health. Doi: 10.3389/fpubh.2015.00202.
McGregor, G.F., M. Gottschalk, D.L. Godson, W. Wilkins, T.K. Bollinger. 2015. Disease risks associated with free-ranging wild boar in Saskatchewan. Canadian Veterinary Journal. 56: 839-844.
Bai, X., Z. Liu, S. Ji, M. Gottschalk, H. Zheng, J. Xu. 2015. Simultaneous detection of 33 Streptococcus suis serotypes using the luminex xTAG® assay™. Journal of Microbiology Methods. pii: S0167- 7012(15)30026-9.
Atanassov, C., L. Bonifait, M. Perivier, M. Gottschalk, D. Grenier. 2015. Candidate proteomic biomarkers for three genogroups of the swine pathogen Streptococcus suis serotype 2. BMC Microbiology. 15: 84.
Zheng, H., S. Ji, Z. Liu, R. Lan, Y. Huang, X. Bai, M. Gottschalk, J. Xu. 2015. Eight novel capsular polysaccharide synthesis gene loci identified in nontypeable Streptococcus suis isolates. Applied and Environmental Microbiology. 81: 4111-4119.
Roy, D., J.P. Auger, M. Segura, N. Fittipaldi, D. Takamatsu, O. Masatoshi, M. Gottschalk. 2015. Role of the capsular polysaccharide as a virulence factor for Streptococcus suis serotype 14. Canadian Journal of Veterinary Research. 79: 141-146.
Baroch, J.A., C.A. Gagnon, S. Lacouture, M. Gottschalk. 2015. Exposure of f US feral swine (Sus scrofa) in the United States to selected pathogens. Canadian Journal of Veterinary Research. 79: 74-78.
Vaillancourt, K., G. LeBel, M. Frenette, M. Gottschalk, D. Grenier. 2015. Suicin 3908, a new lantibiotic produced by a strain of Streptococcus suis serotype 2 isolated from a healthy carrier pig. Plos ONE. 10: e0117245.
Sánchez Del Rey, V., J.F. Fernández-Garayzábal, C. Bárcena, V. Briones, L. Domínguez, M. Gottschalk, A.I. Vela. 2014. Molecular typing of Streptococcus suis isolates from Iberian pigs: a comparison with isolates from common intensively-reared commercial pig breeds. Veterinary Journal. 202: 597-602.
Calzas, C., P. Lemire, G. Auray, V. Gerdts, M. Gottschalk, M. Segura. 2015. Antibody Response Specific to the Capsular Polysaccharide is Impaired in Streptococcus suis Serotype 2-Infected Animals. Infection and Immunity. 83: 441-453.
Wongsawan, K., M. Gottschalk, P. Tharavichitkul. 2015. Serotype- and virulence-associated gene profile of Streptococcus suis isolates from pig carcasses in Chiang Mai Province, Northern Thailand. Journal of Veterinary Medical Science. 77:233-236.
Muckle, A., A. López, M. Gottschalk, C. López-Méndez, J. Giles, L. Lund, M. Saab. 2014. Isolation of Streptococcus suis from two lambs with history of lameness. Canadian Veterinary Journal. 55: 946-949.
Espinosa, I., M. Áreas, M. Irian Percedo, E. Lobo, S. Martínez, M. Gottschalk. 2014. Serotyping of porcine Streptococcus suis recovered from diseased pigs in the western region of Cuba. Revista de Salud Animal. 36: 196-200.
Zheng, H., S. Ji, R. Lan, Z. Liu, X. Bai, W. Zhang, M. Gotschalk, J. Xu. 2014. Population analysis of Streptococcus suis isolates from slaughtered swine using minimum core genome sequence typing. Journal of Clinical Microbiology. 52: 3568-3572.
Haas B., L. Bonifait, K. Vaillancourt, S.J. Charette, M. Gottschalk, D. Grenier. 2014. Characterization of DNase activity and gene in Streptococcus suis and evidence for a role as virulence factor. BMC Research Notes. 7: 424.
LeBel, G., K. Vaillancourt, M. Frenette, M. Gottschalk, D. Grenier. 2014. Suicin 90-1330 from a nonvirulent strain of Streptococcus suis: a nisin-related lantibiotic active on Gram-positive swine pathogens. Applied and Environmental Microbiology. 80: 5484-5492.
Tharavichitkul, P., K. Wongsawan, N. Takenami, S. Pruksakorn, A. Fongcom, M. Gottschalk, B. Kanthawa, V. Supajatura, S. Takai. 2014. Correlation between PFGE Groups and Mrp / Epf / Sly Genotypes of Streptococcus Suis Serotype 2 in Northern Thailand. Journal of Pathogens. doi: 10.1155/2014/350416.
Sánchez del Rey, V., J.F. Fernández-Garayzábal, G. Mentaberre, V. Briones, S. Lavín, L. Domínguez, M. Gottschalk, A.I. Vela Alonso. 2014. Characterisation of Streptococcus suis isolates from wild boars (Sus scrofa). Veterinary Journal. 200: 464-467.
Gomez, E., C. Kennedy, M. Gottschalk, S. Cunningham, R. Patel, A. Virk. 2014 A Case of Streptococcus suis Prosthetic Joint Infection and Streptococcal Toxic Shock-like Syndrome in a United States Pig Farmer. Journal of Clinical Microbiology. 52: 2254-2258
Dang, Y., C. Lachance, Y. Wang, C.A. Gagnon, C. Savard, M. Segura, D. Grenier, M. Gottschalk. 2014. Transcriptional approach to study porcine tracheal epithelial cells individually or dually infected with swine influenza virus and Streptococcus suis. BMC Veterinary Research. 10: 86.
Kerdsin, A., Y. Akeda, R. Hatrongjit, U. Detchawna, T. Sekizaki, S. Hamada, M. Gottschalk, K. Oishi. 2014. Streptococcus suis Serotyping by a New Multiplex PCR. Journal of Medical Microbiology. 2014 63: 824-830.
Gottschalk, M., S. Lacouture. 2014. Actinobacillus pleuropneumoniae serotypes 3, 6, 8 and 15 isolated from diseased pigs in North America. Veterinary Record. 174: 452.
Soares, T.C., A.C. Paes, J. Megid, P.E. Ribolla, S. Paduan Kdos, M. Gottschalk. 2014. Antimicrobial susceptibility of Streptococcus suis isolated from clinically healthy swine in Brazil. Canadian Journal of Veterinary Research. 78: 145-149.
Goyette-Desjardins G, Auger JP, Xu J, Segura M, Gottschalk M. Streptococcus suis, an important pig pathogen and emerging zoonotic agent-an update on the worldwide distribution based on serotyping and sequence typing. Emerging microbes & infections. 2014;3(6):e45.
Charlebois A, Marois-Crehan C, Helie P, Gagnon CA, Gottschalk M, Archambault M. Genetic diversity of Mycoplasma hyopneumoniae isolates of abattoir pigs. Veterinary microbiology. 2014;168(2-4):348-56.
Van Calsteren MR, Gagnon F, Calzas C, Goyette-Desjardins G, Okura M, Takamatsu D, et al. Structure determination of Streptococcus suis serotype 14 capsular polysaccharide. Biochemistry and cell biology = Biochimie et biologie cellulaire. 2013;91(2):49-58.
Lachance C, Segura M, Gerber PP, Xu J, Gottschalk M. Toll-like receptor 2-independent host innate immune response against an epidemic strain of Streptococcus suis that causes a toxic shock-like syndrome in humans. PloS one. 2013;8(5):e65031.
Dominguez-Punaro MC, Koedel U, Hoegen T, Demel C, Klein M, Gottschalk M. Severe cochlear inflammation and vestibular syndrome in an experimental model of Streptococcus suis infection in mice. European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology. 2012;31(9):2391-400.
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