Marilène Paquet
- Professeure titulaire
-
Faculté de médecine vétérinaire - Département de pathologie et microbiologie
Tunnel Mapaq - St-hyacinthe office 1.38
Web : ResearchGate
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Affiliations
- Membre – CRRF — Centre de recherche en reproduction et fertilité
- Membre – RQR — Réseau Québécois en reproduction
Education Programs
- Health Sciences
- Health Sciences
- Health Sciences
- Health Sciences
Courses
- DMV2122 Biopathologie vétérinaire
- MMV66751 Séminaires de recherche en sciences vétérinaires 1
- MMV66751 Séminaires de recherche en sciences vétérinaires 1
- MMV66752 Séminaires de recherche en sciences vétérinaires 2
- MMV66752 Séminaires de recherche en sciences vétérinaires 2
- MMV66753 Séminaires de recherche en sciences vétérinaires 3
- MMV66753 Séminaires de recherche en sciences vétérinaires 3
- MMV70011 Séminaires de recherche en sciences vétérinaires 1
- MMV70011 Séminaires de recherche en sciences vétérinaires 1
- MMV70012 Séminaires de recherche en sciences vétérinaires 2
- MMV70012 Séminaires de recherche en sciences vétérinaires 2
- MMV70013 Séminaires de recherche en sciences vétérinaires 3
- MMV70013 Séminaires de recherche en sciences vétérinaires 3
- MMV70014 Séminaires de recherche en sciences vétérinaires 4
- MMV70014 Séminaires de recherche en sciences vétérinaires 4
- MMV70015 Séminaires de recherche en sciences vétérinaires 5
- MMV70016 Séminaires de recherche en sciences vétérinaires 6
- MMV70016 Séminaires de recherche en sciences vétérinaires 6
Expertises
- Pathologie animale
- Animal Reproduction
- Médecine comparée
- Environnement sain
- Physiologie de la reproduction
- Physiologie animale
Student supervision Expand all Collapse all
Research projects Expand all Collapse all
Regulation of gonadotropin action by Slit/Robo signaling in the mammalian orary Projet de recherche au Canada / 2018 - 2028
Deciphering the role of the nuclear receptor LRH-1 in the establishment of a specific transcriptional program in triple negative breast cancer. Projet de recherche au Canada / 2018 - 2024
Negative Pressure Wound Therapy (NPWT) for open, contaminated wounds in horses Projet de recherche au Canada / 2016 - 2018
Hippo pathway dysregulation in canine mammary gland tumorigenesis and it's potential as a novel therapeutic target Projet de recherche au Canada / 2016 - 2017
Publications Expand all Collapse all
Manteghi S, Gingras MC, Kharitidi D, Galarneau L, Marques M, Yan M, et al. Haploinsufficiency of the ESCRT Component HD-PTP Predisposes to Cancer. Cell reports. 2016;15(9):1893-900.
Boyer A, Girard M, Thimmahahalli DS, Levasseur A, Celeste C, Paquet M, et al. mTOR Regulates Gap Junction Alpha-1 Protein Trafficking in Sertoli Cells and Is Required for the Maintenance of Spermatogenesis in Mice. Biology of reproduction. 2016.
Labbe DP, Uetani N, Vinette V, Lessard L, Aubry I, Migon E, et al. PTP1B Deficiency Enables the Ability of a High-Fat Diet to Drive the Invasive Character of PTEN-Deficient Prostate Cancers. Cancer research. 2016;76(11):3130-5.
Lee T, Paquet M, Larsson O, Pelletier J. Tumor cell survival dependence on the DHX9 DExH-box helicase. Oncogene. 2016. doi: 10.1038/onc.2016.52. [Epub ahead of print].
Allaire JM, Roy SA, Ouellet C, Lemieux E, Jones C, Paquet M, et al. Bmp signaling in colonic mesenchyme regulates stromal microenvironment and protects from polyposis initiation. International journal of cancer. 2016;138(11):2700-12.
Buensuceso AV, Son AI, Zhou R, Paquet M, Withers BM, Deroo BJ. Ephrin-A5 Is Required for Optimal Fertility and a Complete Ovulatory Response to Gonadotropins in the Female Mouse. Endocrinology. 2016;157(2):942-55.
Abedini A, Zamberlam G, Lapointe E, Tourigny C, Boyer A, Paquet M, et al. WNT5a is required for normal ovarian follicle development and antagonizes gonadotropin responsiveness in granulosa cells by suppressing canonical WNT signaling. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 2016;30(4):1534-47.
Nadeau ME, Rico C, Tsoi M, Vivancos M, Filimon S, Paquet M, et al. Pharmacological targeting of valosin containing protein (VCP) induces DNA damage and selectively kills canine lymphoma cells. BMC cancer. 2015;15:479.
Hai L, McGee SR, Rabideau AC, Paquet M, Narayan P. Infertility in Female Mice with a Gain-of-Function Mutation in the Luteinizing Hormone Receptor Is Due to Irregular Estrous Cyclicity, Anovulation, Hormonal Alterations, and Polycystic Ovaries. Biology of reproduction. 2015;93(1):16.
Boerboom D, Kumar V, Boyer A, Wang Y, Lambrot R, Zhou X, et al. beta-catenin stabilization in gonadotropes impairs FSH synthesis in male mice in vivo. Endocrinology. 2015;156(1):323-33.
Stodden GR, Lindberg ME, King ML, Paquet M, MacLean JA, Mann JL, et al. Loss of Cdh1 and Trp53 in the uterus induces chronic inflammation with modification of tumor microenvironment. Oncogene. 2015;34(19):2471-82.
Dauphinee SM, Richer E, Eva MM, McIntosh F, Paquet M, Dangoor D, et al. Contribution of increased ISG15, ISGylation and deregulated type I IFN signaling in Usp18 mutant mice during the course of bacterial infections. Genes and immunity. 2014;15(5):282-92.
Xu E, Forest MP, Schwab M, Avramoglu RK, St-Amand E, Caron AZ, et al. Hepatocyte-specific Ptpn6 deletion promotes hepatic lipid accretion, but reduces NAFLD in diet-induced obesity: potential role of PPARgamma. Hepatology (Baltimore, Md). 2014;59(5):1803-15.
Ramdzan ZM, Vadnais C, Pal R, Vandal G, Cadieux C, Leduy L, et al. RAS transformation requires CUX1-dependent repair of oxidative DNA damage. PLoS biology. 2014;12(3):e1001807.
Shio MT, Paquet M, Martel C, Bosschaerts T, Stienstra S, Olivier M, et al. Drug delivery by tattooing to treat cutaneous leishmaniasis. Scientific reports. 2014;4:4156.
Eva MM, Yuki KE, Dauphinee SM, Schwartzentruber JA, Pyzik M, Paquet M, et al. Altered IFN-gamma-mediated immunity and transcriptional expression patterns in N-Ethyl-N-nitrosourea-induced STAT4 mutants confer susceptibility to acute typhoid-like disease. Journal of immunology (Baltimore, Md : 1950). 2014;192(1):259-70.
Lapointe E, Boyer A, Rico C, Paquet M, Franco HL, Gossen J, et al. FZD1 regulates cumulus expansion genes and is required for normal female fertility in mice. Biology of reproduction. 2012;87(5):104.
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