Pascal Vachon
- Professeur honoraire
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Faculté de médecine vétérinaire - Département de biomédecine vétérinaire
Web : ResearchGate
B.Sc.
1982
, Kinésiologie , Université de Waterloo (Canada)
M.Sc.
1984
, Kinanthropologie , Université de Sherbrooke (Canada)
Ph.D.
1991
, Neurosciences , Université de Montréal (Canada)
D.M.V.
1992
, Université de Montréal (Canada)
Diplomé du ACLAM
2003
, American College of Laboratory Animal Medicine (États-Unis)
Expertises
- Sciences neurologiques
- Médecine comparée
- Recherche translationnelle
- Pharmacology
- Bien-être animal
Responsabilities and outreach Expand all Collapse all
Student supervision Expand all Collapse all
Cycle : Master's
Grade : M. Sc.
Cycle : Master's
Grade : M. Sc.
Cycle : Doctoral
Grade : Ph. D.
Publications Expand all Collapse all
Parent-Vachon M, Beaudry F, Carrier D, Di Cristo G, Vachon P. The effects of exercise on pain and reproductive performance in female pregnant mice with neuropathic pain. Biol Res Nurs 21:.500-509, 2019.
Parent-Vachon M, Vachon P. Environmental enrichment relieves chronic pain in rats following a spared nerve injury to induce neuropathic pain. A preliminary study. Vet Med 9:69-72, 2018.
Saine L, Hélie P, Vachon P. Effects of fentanyl on pain and motor behaviors following a collagenase-induced intracerebral hemorrhage in rats. J Pain Res 9: 1039-1048, 2016.
Dodelet-Devillers A, Zullian C, Beaudry F, Gourdon J, Chevrette J, Hélie P, Vachon P. Physiological and pharmacokinetic effects of multilevel caging on Sprague Dawley rats under ketamine-xylazine anesthesia. Experimental Animals 65 (4) 2016.
Zullian C, Lema P, Lavoie M, Dodelet-Devillers A, Beaudry F, Vachon P. Plasma concentrations of buprenorphine following a single subcutaneous administration of a sustained release formulation of buprenorphine in sheep. Canadian journal of veterinary research - Revue canadienne de recherche veterinaire. 2016;80(3):250-3.
Salmin SF, Giroux MC, Vachon P, Beaudry F. In Vitro Metabolism of Specific CYP2D and CYP3A Opioid Substrates using Rat Liver S9 Fractions and Mass Spectrometry Reveal a Severe Metabolic Impairment with Increasing Age. Biomedical chromatography : BMC. 2016.
Giroux MC, Santamaria R, Helie P, Burns P, Beaudry F, Vachon P. Physiological, pharmacokinetic and liver metabolism comparisons between 3-, 6-, 12- and 18-month-old male Sprague Dawley rats under ketamine-xylazine anesthesia. Experimental animals 2016;65(1):63-75.
Dodelet-Devillers A, Zullian C, Vachon P, Beaudry F. Assessment of stability of ketamine-xylazine preparations with or without acepromazine using high performance liquid chromatography-mass spectrometry. Canadian journal of veterinary research = Revue canadienne de recherche veterinaire. 2016;80(1):86-9.
Zullian C, Dodelet-Devillers A, Roy S, Hélie P, Vachon P. Abdominal distension associated with luminal fungi in the intestines of axolotl larvae. Case Reports Vet Med, Art. ID 851689, 2015.
Prefontaine L, Helie P, Vachon P. Postoperative pain in Sprague Dawley rats after liver biopsy by laparotomy versus laparoscopy. Lab animal. 2015;44(5):174-8.
Menard AL, Grimard G, Londono I, Beaudry F, Vachon P, Moldovan F, et al. Bone growth resumption following in vivo static and dynamic compression removals on rats. Bone. 2015;81:662-8.
Jafari L, Vachon P, Beaudry F, Langelier E. Histopathological, biomechanical, and behavioral pain findings of Achilles tendinopathy using an animal model of overuse injury. Physiological reports. 2015;3(1).
Giroux MC, Helie P, Burns P, Vachon P. Anesthetic and pathological changes following high doses of ketamine and xylazine in Sprague Dawley rats. Experimental animals 2015;64(3):253-60.
Benoit A, Mustafy T, Londono I, Beaudry F, Vachon P, Grimard G, et al. Histomorphometry of the newly formed bone after its growth modulation by static and dynamic compression using a rat tail model. Computer methods in biomechanics and biomedical engineering. 2015;18 Suppl 1:1884-5.
Vachon P. Double Decker Enrichment cages have no effect on long term nociception in neuropathic rats but increases exploration while decreasing anxiety-like behaviors. Scandinavian Journal of Laboratory Animal Science,40 (2) 2014.
Vachon P. Hargreaves does not evaluate nociception following a surgical laparotomy in Xenopus leavis frogs. Research in Veterinary Science. 2014;97(2):470-3.
Communications Expand all Collapse all
Présentations orales
2018 Maladies des souris Congrès Ordre des Médecins Vétérinaires du Québec, St-Hyacinthe, Canada
2018 La douleur : un facteur non-négligeable dans les données de recherche Symposium CIPAR Hôpital Sainte-Justine, Montréal, Canada
2016 Journée de formation en animaux de laboratoire, Université Laval, Québec, Canada
Biais associés à l’utilisation des analgésiques en recherche
L’importance de la formulation des drogues en recherche
2016 Utilisation des plantes pour le traitement de la douleur chronique Mardis Actifs, journée organisé par l’Université de Sherbrooke, Québec, Canada
2015 Pain peptides for the validation of the treatment of chronic pain using natural drugs 7ième École d’été en développement du médicament, Université de Montréal
2015 Achilles tendinopathy animal model: Histopathology, behavioural pain and animal welfare CALAS Annual Symposium, Montréal, Canada
2015 Pathologies des grenouilles Xenopus leavis et méthodes de diagnostiques Journée de formation en animaux de laboratoire, Université Laval, Québec, Canada
2014 Identifying the harms and anticipating the benefits of animal research: A pain researcher’s perspective Harm Benefit Analysis in animal studies, FELASA-AALAS conference, Bergen, Norvège
2014 Double Decker Enrichment cages have no effect on long term nociception in neuropathic rats but increase exploration while decreasing anxiety-like behaviors CALAS symposium, Ottawa, Canada et SCAND-LAS meeting, Stockholm, Suède
2014 Utilisation du modèle animal en recherche et Maladies communes des rongeurs : Quel est votre diagnostic ? Journée de formation en animaux de laboratoire, Université Laval, Québec, Canada
Additional Information
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16-05-2005 Les animaux et la science
Les animaux de laboratoire doivent être bien traités. Sinon, c’est la validité de la recherche qui peut être compromise, dit le vétérinaire Pascal Vachon.