Lawrence C. Smith
- Professeur titulaire
-
Faculté de médecine vétérinaire - Département de biomédecine vétérinaire
Pavillon 3200, rue Sicotte - Aile A office 0123-2
Travail 1 : 450 773-8521 #8463
Télécopieur : 450 778-8103
Web : Page professionnelle (faculté,département,école)
Web : Site web de l’unité de recherche
Web : Google Scholar
DVM
1981
, Médecine vétérinaire , UNESP (Brésil)
MSc
1983
, Génétique , University of Edinburgh (Royaume-Uni)
PhD
1989
, Biologie cellulaire , University of Edinburgh (Royaume-Uni)
Affiliations
Expertises
Student supervision Expand all Collapse all
Cycle : Doctoral
Grade : Ph. D.
Research projects Expand all Collapse all
Réseau Québécois en Reproduction Projet de recherche au Canada / 2024 - 2031
Epigenetic remodelling of genomic imprints of embryonic stem cells differentiated into primordial germ-like cells and gamete-like cells in cattle Projet de recherche au Canada / 2024 - 2026
Nuclear-cytoplasmic interactions in mammalian embryos Projet de recherche au Canada / 2020 - 2026
Derivation of germ lineage cells from bovine haploid parthenogenetic embryos Projet de recherche au Canada / 2023 - 2025
Réseau Québecois en Reproduction (RQR) Projet de recherche au Canada / 2017 - 2025
Generation of bovine iBlastoid using high quality bovine naïve pluripotent stem cells Projet de recherche au Canada / 2023 - 2024
Establishment of bovine embryonic cells derived from blastocyst for producing high quality cloned embryo Projet de recherche au Canada / 2019 - 2023
Biparental haploid cells to generate genomically designed offspring Projet de recherche au Canada / 2019 - 2023
Use of haploid embryonic cells to generate offspring with predetermined genomes Projet de recherche au Canada / 2016 - 2023
NUCLEAR-CYTOPLASMIC INTERACTIONS IN MAMMALIAN EMBRYOS Projet de recherche au Canada / 2015 - 2022
Supplément COVID-19 CRSNG_Nuclear-cytoplasmic interactions in mammalian embryos Projet de recherche au Canada / 2020 - 2021
Operations and Maintenance Support for Canadensys: Pancanadian Biodiversity Informatics Network and Portal Projet de recherche au Canada / 2017 - 2019
REGROUPEMENT STRATEGIQUE - RESEAU QUEBECOIS EN REPRODUCTION (RQR) Projet de recherche au Canada / 2011 - 2018
NUCLEAR-CYTOPLASMIC INTERACTIONS IN MAMMALIAN EMBRYOS Projet de recherche au Canada / 1994 - 2016
TRAINING IN REPRODUCTIVE BIOLOGY Projet de recherche au Canada / 2009 - 2015
CHAIRE DE RECHERCHE DU CANADA - ANIMAL CLONING AND STEM CELLS Projet de recherche au Canada / 2008 - 2015
Nuclear cytoplasmic interactions in mammalian embryos Projet de recherche au Canada / 2009 - 2014
PROJET PILOTE TRAUMANET QUEBEC - COMPARISON OF MESENCHYMAL (MSC) AND INDUCED PLURIPOTENT (IPS) STEM CELLS FOR CARTILAGE REPAIR FOLLOWING TRAUMA Projet de recherche au Canada / 2012 - 2013
Publications Expand all Collapse all
Aguiar C, Therrien J, Lemire P, Segura M, Smith LC, Theoret CL. Differentiation of equine induced pluripotent stem cells into a keratinocyte lineage. Equine veterinary journal. 2016;48(3):338-45.
Smith LC, Therrien J, Filion F, Bressan F, Meirelles FV. Epigenetic consequences of artificial reproductive technologies to the bovine imprinted genes SNRPN, H19/IGF2, and IGF2R. Frontiers in genetics. 2015;6:58.
Machado TS, Macabelli CH, Sangalli JR, Rodrigues TB, Smith LC, Meirelles FV, et al. Real-Time PCR Quantification of Heteroplasmy in a Mouse Model with Mitochondrial DNA of C57BL/6 and NZB/BINJ Strains. PloS one. 2015;10(8):e0133650.
Bavin EP, Smith O, Baird AE, Smith LC, Guest DJ. Equine Induced Pluripotent Stem Cells have a Reduced Tendon Differentiation Capacity Compared to Embryonic Stem Cells. Frontiers in veterinary science. 2015;2:55.
Aguiar C, Theoret C, Smith O, Segura M, Lemire P, Smith LC. Immune potential of allogeneic equine induced pluripotent stem cells. Equine veterinary journal. 2015;47(6):708-14.
Biase FH, Everts RE, Oliveira R, Santos-Biase WK, Fonseca Merighe GK, Smith LC, et al. Messenger RNAs in metaphase II oocytes correlate with successful embryo development to the blastocyst stage. Zygote (Cambridge, England). 2014;22(1):69-79.
Verduzco A, Fecteau G, Lefebvre R, Smith LC, Murphy BD. Expression of steroidogenic proteins in bovine placenta during the first half of gestation. Reproduction, fertility, and development. 2012;24(2):392-404.
Smith LC, Suzuki J, Jr., Goff AK, Filion F, Therrien J, Murphy BD, et al. Developmental and epigenetic anomalies in cloned cattle. Reproduction in domestic animals = Zuchthygiene. 2012;47 Suppl 4:107-14.
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